Open AccessPsoriasis as a Model for T-Cell–Mediated Disease
Author(s) -
Alice B. Gottlieb,
James G. Krueger,
Knut M. Wittkowski,
Russell L. Dedrick,
Patricia A. Walicke,
Marvin R. Garovoy
Publication year - 2002
Publication title -
archives of dermatology
Language(s) - English
Resource type - Journals
eISSN - 1538-3652
pISSN - 0003-987X
DOI - 10.1001/archderm.138.5.591
Subject(s) - psoriasis , efalizumab , medicine , psoriasis area and severity index , cd11a , immunology , gastroenterology , monoclonal antibody , antibody , cd18 , plaque psoriasis
Leukocyte function-associated antigen 1 (LFA-1), consisting of CD11a and CD18 subunits, plays an important role in T-cell activation and leukocyte extravasation.
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