Clinical and Serological Transition From Pemphigus Vulgaris to Pemphigus Foliaceus Demonstrated by Desmoglein ELISA System
Author(s) -
Yukiko Tsuji,
Toshimitsu Kawashima,
Koichi Yokota,
Yasuki Tateish,
Yuki Tomita,
Tetsuri Matsumura,
Hiroshi Shimizu
Publication year - 2002
Publication title -
archives of dermatology
Language(s) - English
Resource type - Journals
eISSN - 1538-3652
pISSN - 0003-987X
DOI - 10.1001/archderm.138.1.95
Subject(s) - pemphigus foliaceus , desmoglein 1 , pemphigus vulgaris , medicine , dermatology , serology , desmoglein 3 , desmoglein , immunology , autoantibody , antibody
everal cases in which the disease course has undergone a transition from pemphigus vulgaris (PV) to pemphigus foliaceus (PF) or vice versa have been reported in the lit- erature. The disease transition in these cases was determined by means of clinical and histopathological observations and immunoblot analysis. To our knowledge, the case described herein represents the first report to clearly demonstrate the serological transition from mucous PV to mucocutaneous PV to PF using a desmoglein (Dsg) enzyme-linked immunosorbent assay (ELISA) system.
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