Open AccessSoluble Interleukin 2 Receptor and Interleukin 1α in Toxic Epidermal Necrolysis
Author(s) -
Osvaldo Correia,
Luís Delgado,
JeanClaude Roujeau,
Laurence Le Cleach,
José A. Fleming-Torrinha
Publication year - 2002
Publication title -
archives of dermatology
Language(s) - English
Resource type - Journals
eISSN - 1538-3652
pISSN - 0003-987X
DOI - 10.1001/archderm.138.1.29
Subject(s) - toxic epidermal necrolysis , blisters , medicine , interleukin 2 , interleukin , keratinocyte , tumor necrosis factor alpha , cd8 , toxicity , receptor , necrosis , cytokine , immunology , dermatology , immune system , biology , cell culture , genetics
Toxic epidermal necrolysis (TEN) is a rare but severe adverse drug disease, characterized by extensive skin and mucosal detachment with participation of different immunoinflammatory pathways, in particular with early participation of activated CD8+ T lymphocytes.
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