Solitary Melanoma Confined to the Dermal and/or Subcutaneous Tissue | Zendy

Glen M. Bowen | Zendy; Alfred E. Chang | Zendy; Lori Lowe | Zendy; Ted A. Hamilton | Zendy; Rupa Patel | Zendy; Timothy M. Johnson | Zendy

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Solitary Melanoma Confined to the Dermal and/or Subcutaneous Tissue

Author(s) -

Glen M. Bowen,

Alfred E. Chang,

Lori Lowe,

Ted A. Hamilton,

Rupa Patel,

Timothy M. Johnson

Publication year - 2000

Publication title -

archives of dermatology

Language(s) - English

Resource type - Journals

eISSN - 1538-3652

pISSN - 0003-987X

DOI - 10.1001/archderm.136.11.1397

Subject(s) - medicine , melanoma , population , stage (stratigraphy) , cancer , confidence interval , dermatology , survival analysis , oncology , ajcc staging system , pathology , staging system , paleontology , environmental health , cancer research , biology

Several patients presented with a single focus of presumed cutaneous metastatic melanoma with an unknown primary tumor based on clinical and histologic staging criteria of the American Joint Committee on Cancer (AJCC). This population is classified as having stage IV disease by the current AJCC staging system, which carries a dismal prognosis (5%-18% 5-year survival). Our clinical observation was that these patients had a higher survival rate than would be expected for stage IV disease. We believe this population represents a subgroup of primary dermal- and or subcutaneously-derived melanoma that simulates cutaneous metastatic melanoma in histologic and clinical presentation but may differ in behavior.

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