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Zonisamide for Weight Reduction in Obese Adults
Author(s) -
Kishore M. Gadde,
Mariko F. Kopping,
Henry R. Wagner,
Gretchen M. Yonish,
David B. Allison,
George A. Bray
Publication year - 2012
Publication title -
archives of internal medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3679
pISSN - 0003-9926
DOI - 10.1001/2013.jamainternmed.99
Subject(s) - zonisamide , medicine , placebo , weight loss , body mass index , tolerability , canagliflozin , dosing , obesity , randomized controlled trial , diabetes mellitus , topiramate , adverse effect , type 2 diabetes , endocrinology , epilepsy , alternative medicine , pathology , psychiatry
Obese individuals who have failed to achieve adequate weight loss with lifestyle changes have limited nonsurgical therapeutic options. We evaluated the efficacy and tolerability of zonisamide, an antiepileptic drug, for enhancing weight loss in obese patients receiving diet and lifestyle guidance.

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