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Comparison of Physician-, Biomarker-, and Symptom-Based Strategies for Adjustment of Inhaled Corticosteroid Therapy in Adults With Asthma
Author(s) -
William J. Calhoun,
Bill T. Ameredes,
Tonya S. King,
Nikolina Icitovic,
Eugene R. Bleecker,
Mario Castro,
Reuben M. Cherniack,
Ver M. Chinchilli,
Timothy Craig,
Loren C. Denlinger,
Emily DiMango,
Linda Engle,
John V. Fahy,
J. A. Grant,
Elliot Israel,
Nizar N. Jarjour,
Shamsah Kazani,
Monica Kraft,
Susan J. Kunselman,
Stephen C. Lazarus,
Robert F. Lemanske,
Njira Lugogo,
Richard J. Martin,
Deborah A. Meyers,
Wendy C. Moore,
Rodolfo M. Pascual,
Stephen P. Peters,
Joe Ramsdell,
Christine A. Sorkness,
E. Rand Sutherland,
Stanley J. Szefler,
Stephen I. Wasserman,
Michael Walter,
Michael E. Wechsler,
Homer A. Boushey
Publication year - 2012
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/2012.jama.10893
Subject(s) - medicine , exhaled nitric oxide , asthma , guideline , corticosteroid , randomized controlled trial , placebo , biomarker , pediatrics , physical therapy , intensive care medicine , spirometry , alternative medicine , pathology , biochemistry , chemistry
No consensus exists for adjusting inhaled corticosteroid therapy in patients with asthma. Approaches include adjustment at outpatient visits guided by physician assessment of asthma control (symptoms, rescue therapy, pulmonary function), based on exhaled nitric oxide, or on a day-to-day basis guided by symptoms.

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