Association of Clopidogrel Treatment With Risk of Mortality and Cardiovascular Events Following Myocardial Infarction in Patients With and Without Diabetes
Author(s) -
Charlotte Andersson,
Stig Lyngbæk,
Cu Dinh Nguyen,
Mia Nielsen,
Gunnar Gislason,
Lars Køber,
Christian TorpPedersen
Publication year - 2012
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/2012.jama.10779
Subject(s) - medicine , clopidogrel , diabetes mellitus , hazard ratio , myocardial infarction , cardiology , type 2 diabetes , comorbidity , confidence interval , endocrinology
Pharmacodynamic studies have shown that persistently high platelet reactivity is common in patients with diabetes in spite of clopidogrel treatment. Clinical trials have not convincingly demonstrated that clopidogrel benefits patients with diabetes as much patients without diabetes.
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