Open AccessLight Chain Myeloma induced Severe Hypertriglyceridemia
Author(s) -
Shafeeque Rahman,
Prabhat Kumar,
Subodh Kumar Mahto,
Rajinder Singh Tonk,
Rajesh Taneja
Publication year - 2017
Publication title -
journal of clinical and diagnostic research
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2017/24476.9360
Subject(s) - hypertriglyceridemia , medicine , multiple myeloma , hyperlipidemia , gastroenterology , triglyceride , acute pancreatitis , diabetes mellitus , endocrinology , cholesterol
Hyperlipidemia is very common in general population and incidence has further increased in recent years. Evaluation of patient presenting with lipid disorders is essential to obtain a definite diagnosis to prevent complications, and apply the most appropriate treatment. An isolated elevation in triglyceride levels may be caused by a primary disorder of lipid metabolism like familial hypertriglyceridemia. It may also arise secondary to a number of conditions like diabetes mellitus, alcohol intake, hypothyroidism, drugs, infections and nephrotic syndrome. Herein, we describe a case of secondary hypertriglyceridemia leading to Nonalcoholic Steatohepatitis (NASH) in a young female which was attributed to Multiple Myeloma (MM). Significant reduction in triglyceride levels after starting anti-myeloma therapy established their relation. This is the first case of light chain myeloma causing severe secondary hypertriglyceridemia.