Open AccessStudy of Immunohistochemical Markers (CK-19, CD-56, Ki-67, p53) in Differentiating Benign and Malignant Solitary Thyroid Nodules with special Reference to Papillary Thyroid Carcinomas
Author(s) -
Smriti S Dwivedi,
Siddhi Gaurish Sinai Khandeparkar,
Avinash R Joshi,
M. L. Kulkarni,
Pallavi D Bhayekar,
Amruta B Jadhav,
Musphera Nayar,
Neelam S Kambale
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/22428.9114
Subject(s) - immunohistochemistry , pathology , thyroid nodules , thyroid , papillary carcinoma , medicine , thyroid tumors , thyroid carcinoma , p53 protein
Solitary Thyroid Nodule (STN) has provoked increased concern owing to higher incidence of malignancy. The inter and intra observer variation in the histomorphological diagnosis of Papillary Thyroid Carcinomas (PTC) may sometimes pose a diagnostic difficulty.