Open AccessIn Vivo Autofluorescence Spectroscopic Study and Evaluation of DNA Damage By Comet Assay in Smokers
Author(s) -
M Rajmohan,
Radhakrishnan Murali Naidu,
D Thamaraiselvi,
M. Deepasree
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/13805.5874
Subject(s) - comet assay , autofluorescence , dna damage , in vivo , pathology , lesion , medicine , microbiology and biotechnology , carcinogen , comet tail , chemistry , dna , fluorescence , biology , genetics , biochemistry , physics , optics , quantum mechanics , magnetic field , solar wind
Tobacco is known environmental factor to alter the chemical composition of cells and the structure of DNA. Cellular level changes of smoker's mucosa are assessed by autofluorescence spectroscopy and the DNA damage can be evaluated by single cell gel electrophoresis (comet assay).