Open AccessRole of Cytochrome Modulators in Altering the Occurrence of Cataract in Rats
Author(s) -
Kumkum Gupta,
Shivani Juneja,
Gurkirat Singh Bajwa,
Sandeep Kaushal
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/12411.6216
Subject(s) - medicine , cataracts , ciprofloxacin , phenytoin , inducer , pharmacology , endocrinology , ophthalmology , antibiotics , biochemistry , biology , epilepsy , psychiatry , gene
Cataract is one of the primary causes of blindness all over the world. It indicates the onset of secondary complications of diabetes. The only treatment available is surgery as there are no satisfactory drugs which can prevent or retard the initiation and maturation of cataract. It was hypothesized that cytochrome P 450 (CYP) inducers or inhibitors can modify the cataract occurrence by accelerating or delaying the occurrence of cataract respectively.