Open AccessPerformance of a Rapid Strip Test for the Serologic Diagnosis of Latent Tuberculosis in Children
Author(s) -
Songsri Kasempimolporn,
Wichit Thaveekarn,
Phirangkool Kerdpanich,
U Skulpichetrat,
O Saekhow,
Supatsorn Boonchang,
Thipchuta Bharnthong,
Sitprija
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/10989.5403
Subject(s) - medicine , tuberculin , active tuberculosis , tuberculosis , serology , latent tuberculosis , diagnostic test , interferon gamma release assay , skin test , interferon γ , gold standard (test) , diagnostic accuracy , tuberculosis diagnosis , immunology , mycobacterium tuberculosis , pediatrics , interferon gamma , antibody , pathology , cytokine
The serodiagnostic tests for tuberculosis (TB) present a high variability in terms of sensitivity and specificity. Data on patients with latent TB infection (LTBI) and children in high prevalence settings are still limited. The present study aimed to evaluate an in-house strip test for detection of anti-M. tuberculosis antibodies in TB patients, mostly children aged under 15 y, grouped into four diagnostic categories: active TB, LTBI, healthy TB contacts, and other non-TB diseases.