Open AccessPentoxifylline: A New Armamentarium in Diabetic Foot Ulcers
Author(s) -
Venkatesh Rewale,
Kiran Ravi Prabhakar,
Anjali Chitale
Publication year - 2014
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2014/7856.3984
Subject(s) - pentoxifylline , medicine , microcirculation , diabetic foot , blood flow , diabetes mellitus , ambulatory , surgery , intermittent claudication , vascular disease , arterial disease , endocrinology
Diabetic foot ulcers are estimated to affect 15% of all diabetics and precede almost 85% of foot amputations. Pentoxyfylline a substituted xanthenes' derivative has been reported to increase the blood flow to the microcirculation and enhances tissue oxygenation. It has been widely used in the treatment of intermittent claudication.