Open AccessImmunohistochemical Expression of PCNA in Epithelial Linings of Selected Odontogenic Lesions
Author(s) -
T Shahela,
Syeda Aesha,
Kannan Ranganathan,
Roa K,
Elizabeth Joshua,
Ashir Ahmed,
Harika Chittamsetty
Publication year - 2013
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2013/5824.3629
Subject(s) - keratocyst , ameloblastoma , dentigerous cyst , radicular cyst , pathology , proliferating cell nuclear antigen , cyst , immunohistochemistry , odontogenic , biology , odontogenic cyst , medicine , anatomy , maxilla
Though odontogenic lesions have in common origin from the primitive odontogenic epithelium , there is a diversity in their initiation behavior and growth. The aggressive nature of odontogenic keratocyst similar to ameloblastoma in comparision with the other common odontogenic (dentigerous and radicular) cyst could be due to possible differences in their epithelial linings. PCNA (Proliferating cell nuclear antigen) is a cell cycle related antigen, used in the study of cell kinetics of these epithelial linings, to corelate the biological behaviour among these common odontogenic lesions.