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In the present study, meningococcal serogroup B outer membrane vesicles (OMVs) were associated with bilayer fragments of a cationic lipid, dioctadecyldimethylammonium (DDA-BF), used as adjuvant, in an antigenic preparation tested in adult female outbred mice. This adjuvant was compared to the traditional adjuvant aluminum hydroxide.

clinical and experimental vaccine research

Immunogenicity of antigens from outer membrane vesicles of <i>Neisseria meningitidis</i> associated with bilayer fragment of dioctadecyldimethylammonium in Swiss adult mice

Immunogenicity of antigens from outer membrane vesicles of Neisseria meningitidis associated with bilayer fragment of dioctadecyldimethylammonium in Swiss adult mice