Open AccessResults of Frequency Analysis Distribution of Polymorphism Rs1800895 592C>A In IL10 Gene among Patients with Chronic Polypoid Rhinosinusitis.
Author(s) -
Jamolbek Abdukakhorovich Djuraev,
У.С. Хасанов,
Vokhidov Ulugbek Nuridinovuch,
Shaumarov Azizkhon Zavkievich
Publication year - 2022
Publication title -
pubmed
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 30
ISSN - 0946-5448
DOI - 10.5935/0946-5448.20210032
Subject(s) - medicine , genotype , nasal polyps , gastroenterology , chronic rhinosinusitis , disease , nose , immunology , pathology , surgery , gene , biology , genetics
Chronic polyposis rhinosinusitis is a disease characterized by chronic inflammation of the nasal mucosa and sinuses. In the tissues of polyps and intranasal secretions, an increase in the concentration of various inflammatory mediators, in particular interleukins is observed due to an increase in their de novo synthesis by effector cells. The research objective to study the distribution of genotypic forms of the IL10 gene locus and evaluate their role in the development and clinical course of chronic polypoid rhinosinusitis.
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