Open AccessKidney injury in COVID-19
Author(s) -
Adeel Ahmed,
Chaudhry Adeel Ebad,
Sinéad Stoneman,
Muniza Manshad Satti,
Peter J. Conlon
Publication year - 2020
Publication title -
world journal of nephrology
Language(s) - Uncategorized
Resource type - Journals
ISSN - 2220-6124
DOI - 10.5527/wjn.v9.i2.18
Subject(s) - medicine , acute kidney injury , cytokine storm , covid-19 , kidney , incidence (geometry) , intensive care medicine , autopsy , diffuse alveolar damage , epidemiology , pathophysiology , ards , acute respiratory distress , kidney disease , respiratory distress , disease , pathology , lung , infectious disease (medical specialty) , surgery , physics , optics
Coronavirus disease 2019 (COVID-19) continues to affect millions of people around the globe. As data emerge, it is becoming more evident that extrapulmonary organ involvement, particularly the kidneys, highly influence mortality. The incidence of acute kidney injury has been estimated to be 30% in COVID-19 non-survivors. Current evidence suggests four broad mechanisms of renal injury: Hypovolaemia, acute respiratory distress syndrome related, cytokine storm and direct viral invasion as seen on renal autopsy findings. We look to critically assess the epidemiology, pathophysiology and management of kidney injury in COVID-19.