Open AccessBroad spectrum of interferon-related nephropathies-glomerulonephritis, systemic lupus erythematosus-like syndrome and thrombotic microangiopathy: A case report and review of literature
Author(s) -
Iacopo Gianassi,
Marco Allinovi,
Leonardo Caroti,
Lino Cirami
Publication year - 2019
Publication title -
world journal of nephrology
Language(s) - English
Resource type - Journals
ISSN - 2220-6124
DOI - 10.5527/wjn.v8.i7.109
Subject(s) - medicine , thrombotic microangiopathy , eculizumab , microangiopathy , immunology , nephropathy , atypical hemolytic uremic syndrome , kidney , dialysis , systemic lupus erythematosus , glomerulonephritis , antiphospholipid syndrome , gastroenterology , dermatology , complement system , antibody , endocrinology , disease , diabetes mellitus
Interferons (IFNs) are characterized by a wide range of biological effects, which justifies their potential therapeutic use in several pathologies, but also elicit a wide array of adverse effects in almost every organ system. Among them, renal involvement is probably one of the most complex to identify.