Open AccessSerum Levels of Tumor Necrosis Factor - alpha in Patients With Psoriasis
Author(s) -
Nermina Ovcina Kurtovic,
Emina Kasumagic Halilovic
Publication year - 2022
Publication title -
materia socio-medica/materia socio medica
Language(s) - English
Resource type - Journals
eISSN - 1986-597X
pISSN - 1512-7680
DOI - 10.5455/msm.2022.33.40-43
Subject(s) - psoriasis , medicine , psoriasis area and severity index , tumor necrosis factor alpha , psoriatic arthritis , gastroenterology , cytokine , immunology , severity of illness , dermatology
Psoriasis can be described as a T-cell-mediated disease, with a complex role for variety of cytokines and other factors. Among the inflammatory molecules influencing the keratinocites, TNF-α appears critical in sustaining most of the clinical manifestations of psoriasis. It is postulated that changes in cytokine production both locally and systemically could be useful in monitoring disease activity.