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Myalgia reflects generalized inflammation and cytokine response and can be the onset symptom of 36% of patients with COVID-19. Interleukin-6 (IL-6) and tumor necrosis factor-α (TNF- α) levels in plasma and upper respiratory secretions directly correlate with the magnitude of viral replication, fever, and respiratory and systemic symptoms, including musculoskeletal clinical manifestations.

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Dexamethasone and Nutraceutical Therapy Can Reduce the Myalgia Due to COVID-19 "&amp;#".ord($0).";""&amp;#".ord($0).";""&amp;#".ord($0).";" a Systemic Review of the Active Substances that Can Reduce the Expression of Interlukin-6