Open AccessA rare case of accelerated gingival overgrowth with high dose amlodipine therapy
Author(s) -
B M Rakesh,
Sahithi Sharma,
K H Chandana
Publication year - 2021
Publication title -
journal of pharmacovigilance and drug research
Language(s) - English
Resource type - Journals
ISSN - 2582-7235
DOI - 10.53411/jpadr.2021.2.1.8
Subject(s) - amlodipine , nifedipine , medicine , calcium channel , gingivectomy , calcium channel blocker , drug , gingival enlargement , side effect (computer science) , hyperplasia , calcium , dermatology , dentistry , pharmacology , blood pressure , computer science , programming language
Gingival overgrowth represents an over-exuberant response to a variety of local and systemic conditions. Certain anticonvulsants, immunosuppressive drugs, and a number of calcium channel blockers have been shown to produce similar gingival overgrowth in susceptible patients.
Case report: We report a case of accelerated drug-induced gingival overgrowth in a 60-year-old hypertensive patient taking amlodipine at a dose of 10 mg.
Conclusions: Among the calcium channel blockers, nifedipine is most frequently associated with gingival overgrowth. Whereas, there is limited evidence of amlodipine-induced gingival hyperplasia.