Open AccessDiagnostic role of Xpert-MTB RIF assay in osteoarticular tuberculosis: A retrospective study
Author(s) -
Monalisa Mohanty,
Baijayantimala Mishra,
Mantu Jain,
Lubaib Karaniveed Puthiyapura
Publication year - 2022
Publication title -
world journal of orthopedics
Language(s) - English
Resource type - Journals
ISSN - 2218-5836
DOI - 10.5312/wjo.v13.i3.289
Subject(s) - medicine , tuberculosis , extrapulmonary tuberculosis , retrospective cohort study , genexpert mtb/rif , mycobacterium tuberculosis , pediatrics , surgery , pathology
Osteoarticular tuberculosis (OATB) is a severe form of extrapulmonary tuberculosis (TB), which causes notable morbidity and warrants a high index of suspicion for prompt management. The diagnosis of OATB poses a challenge, because of the difficulty of collecting the samples and, secondarily, the paucibacillary nature of lesion, which gives poor sensitivity and reproducibility, with long turnaround time of routine/conventional laboratory tests and the requirement for invasive procedures and expertise. The Xpert MTB/RIF assay has been approved by the World Health Organization as a rapid diagnostic tool for diagnosing pulmonary and extrapulmonary TB.