Open AccessMismatch repair protein expression and intratumoral budding in rectal cancer are associated with an increased pathological complete response to preoperative chemoradiotherapy: A case-control study
Author(s) -
Leonardo S. LinoSilva,
Armando Gamboa-Domı́nguez,
Diego Zúñiga-Tamayo,
Rosa A. SalcedoHernández,
Lucely Cetina,
David Cantú-de-León
Publication year - 2018
Publication title -
world journal of clinical oncology
Language(s) - English
Resource type - Journals
ISSN - 2218-4333
DOI - 10.5306/wjco.v9.i7.133
Subject(s) - tumor budding , medicine , colorectal cancer , chemoradiotherapy , pathological , adenocarcinoma , oncology , complete response , biopsy , dna mismatch repair , gastroenterology , cancer , pathology , chemotherapy , metastasis , lymph node metastasis
To determine whether the association of rectal adenocarcinoma with a defective-mismatch repair system (dMMR) was associated with a pathological complete response (pCR) to preoperative chemoradiotherapy.