Open AccessRecurrence-free survival as a putative surrogate for overall survival in phase III trials of curative-intent treatment of colorectal liver metastases: Systematic review
Author(s) -
Raphael L. C. Araújo,
Paulo Herman,
Rachel P. Riechelmann
Publication year - 2017
Publication title -
world journal of clinical oncology
Language(s) - English
Resource type - Journals
ISSN - 2218-4333
DOI - 10.5306/wjco.v8.i3.266
Subject(s) - medicine , surrogate endpoint , oncology , hazard ratio , perioperative , colorectal cancer , proportional hazards model , population , clinical trial , clinical endpoint , overall survival , confidence interval , surgery , cancer , environmental health
To verify whether recurrence-free survival (RFS) surrogates overall survival (OS) in phase III trials for resectable colorectal liver metastases (CRLM).