Open AccessHow best to manage gastrointestinal stromal tumor
Author(s) -
Gandhi Lanke,
Jeffrey H. Lee
Publication year - 2017
Publication title -
world journal of clinical oncology
Language(s) - English
Resource type - Journals
ISSN - 2218-4333
DOI - 10.5306/wjco.v8.i2.135
Subject(s) - medicine , pathogenesis , gastrointestinal tract , gist , stromal cell , stromal tumor , tyrosine kinase inhibitor , pathology , radiology , cancer
Gastrointestinal stromal tumors (GISTs) are rare but most common nonepithelial tumor of gastrointestinal tract. They are often found incidentally on computed tomography and endoscopic investigations. Increasing knowledge of the pathogenesis of GISTs and the advent of tyrosine kinase inhibitors revolutionized the management of GISTs. The newer advanced endoscopic techniques have challenged the conventional surgery although the true efficacy and safety of endoscopic approach is not clear at this time. This review article focuses on pathogenesis, diagnosis and management of GISTs.