Open AccessPrognostic role of sarcopenia in metastatic colorectal cancer patients during first-line chemotherapy: A retrospective study
Author(s) -
Chiara De Maddalena,
Andrea Ponsiglione,
Luigi Camera,
Lidia Santarpia,
Fabrizio Pasanisi,
Dario Bruzzese,
Camilla Panico,
Giovanni Fiore,
Simona Camardella,
Tolomeo Caramia,
Alessia Farinaro,
Sabino De Placido,
Chiara Carlomagno
Publication year - 2021
Publication title -
world journal of clinical oncology
Language(s) - English
Resource type - Journals
ISSN - 2218-4333
DOI - 10.5306/wjco.v12.i5.355
Subject(s) - medicine , sarcopenia , colorectal cancer , chemotherapy , retrospective cohort study , oncology , cancer , surgery
Sarcopenia is a condition characterized by decreased skeletal muscle mass due to physiological ageing or to a concomitant disease such as neoplasia. In cancer patients, a low lean body mass is suggested to be a negative prognostic factor for survival and for the development of dose-limiting chemotherapy toxicities irrespective of disease stage.