Open AccessCytotoxic CD8+ T cells and tissue resident memory cells in colorectal cancer based on microsatellite instability and BRAF status
Author(s) -
James Wei Tatt Toh,
Angela Ferguson,
Kevin Spring,
Hema Mahajan,
Umaimainthan Palendira
Publication year - 2021
Publication title -
world journal of clinical oncology
Language(s) - English
Resource type - Journals
ISSN - 2218-4333
DOI - 10.5306/wjco.v12.i4.238
Subject(s) - microsatellite instability , medicine , colorectal cancer , immunohistochemistry , multiplex , pathology , staining , confidence interval , malignancy , cancer , oncology , biology , microsatellite , bioinformatics , genetics , allele , gene
Recent studies in non-colorectal malignancy have associated T resident memory (T RM ) cells with improved patient survival. It is unknown if T RM plays a role in colorectal cancer (CRC).