Open AccessSerum Glial Fibrillary Acidic Protein: A Surrogate Marker of the Activity of Multiple Sclerosis
Author(s) -
Inas K. Sharquie,
Gheyath Al Gawwam,
Shatha F. Abdullah
Publication year - 2020
Publication title -
medeniyet medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.128
H-Index - 4
eISSN - 2149-2042
pISSN - 2149-4606
DOI - 10.5222/mmj.2020.48265
Subject(s) - glial fibrillary acidic protein , multiple sclerosis , exacerbation , cerebrospinal fluid , gastroenterology , medicine , biomarker , receiver operating characteristic , surrogate endpoint , immunology , pathology , chemistry , immunohistochemistry , biochemistry
Multiple sclerosis (MS) is a neurodegenerative disorder with various clinical types. Glial fibrillary acidic protein (GFAP) is significantly elevated in the cerebrospinal fluid (CSF) of MS patients compared with that of healthy controls. The aim of this study is to evaluate serum levels of GFAP in relation to disease activity in relapsing-remitting MS patients and to compare them with those of healthy controls.