Open AccessNasal Plasmablastic Lymphoma in an HIV-Negative Immunocompetent Patient
Author(s) -
Nadhirah Mohd Shakri,
Salina Husain,
Farah Dayana Zahedi,
Geok Chin Tan
Publication year - 2020
Publication title -
medeniyet medical journal
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2149-2042
pISSN - 2149-4606
DOI - 10.5222/mmj.2020.45389
Subject(s) - medicine , plasmablastic lymphoma , human immunodeficiency virus (hiv) , lymphoma , nuclear medicine , chemotherapy , radiology , gastroenterology , virology
Plasmablastic lymphoma (PBL) is a rare and aggressive variant of diffuse large B-cell lymphoma predominantly in oral cavities of human immunodeficiency virus (HIV)-positive male patients or immunosuppressive hosts. Limited number of reports on HIV-negative PBL in immunocompetent patients are available in the literature. We reported an unusual case of sinonasal PBL which occurred in an HIV-negative and immunocompetent female patient. She underwent endoscopic removal of the tumor and completed 6 cycles of chemotherapy (hyperfractionated-CVAD). Any finding in favour of tumour recurrence was not observed in positron-emission tomography scan (PET-scan) performed 18 months after the treatment.