Open AccessSalmonella infections in children: Change of Clinical Characteristics and Antibiotic Resistance Pattern during Years
Author(s) -
Kamile Arıkan,
Gülsüm Biten Güven
Publication year - 2021
Publication title -
forbes tıp dergisi
Language(s) - English
Resource type - Journals
eISSN - 2757-5241
pISSN - 2717-9443
DOI - 10.5222/forbes.2021.57070
Subject(s) - salmonella , ciprofloxacin , ampicillin , medicine , ceftriaxone , serotype , antibiotics , antibiotic resistance , salmonella infection , sulfamethoxazole , trimethoprim , microbiology and biotechnology , gastroenterology , virology , biology , bacteria , genetics
Objective: The aim of this study was to evaluate change of Salmonella infections and antibiotic resistance of patterns in the last 10 years in a tertiary pediatric carecenter in Turkey. Method: In this cross-sectional t study, pediatric patients under 18 years old with complaints of fever and/or acute gastroenteritis and culture positivity of Salmonella spps between January 2009 and July 2019 were included.Clinical characteristics, antibiotic susceptibility tests were recorded. Results: Totally 136 patients,68 (50%) male with a median age of 48.5 months (4-191) were included. Thirteen (9.6%) Salmonella spps were isolated from patients under 1 year old, eighty five (62.5%) under 5 years-old, fifty one (37.5%) above 5 years old of age.Salmonella spps were isolated from stool culture (n=128,94.1%),from urine culture (n=5, 3.7%), 3 (2.2%) from blood culture. Fifty (36.8%) Salmonella spps were isolated between years of 2008-2013, eighty six (63.2%) between years of 2014-2019. The most commonly isolated serogroup was serotype A (25.7%), and serogroup B (3.7%), serogroup C (0.7%) and serogroup D (1.5%) respectively.Antibiotic resistance of Salmonella spps were as follows ampicillin (15.4%), trimethoprim sulfamethaxazole (5.1%), ciprofloxacin (3.7%), cefotaxim (2.2%),ceftriaxone (1.5%),levofloxacine (0.7%) respectively. Conclusions: Increase in cases with Salmonella spp in the last 5 years was noticed. Salmonella infection must be kept in mind in case of acute gastroenteritis, especially in mucous and bloody cases, in children.