Open AccessEffect of Triiodothyronine Administration on the Kidney During Haemorrhagic Shock and Resuscitation
Author(s) -
Iosifina Karmaniolou,
Konstantinos Lamprou,
Chryssoula Staikou,
Evangelos J. GiamarellosBourboulis,
Kassiani Theodoraki,
Αpostolos Papalois,
Anastasios Mylonas,
Nikolaos Orfanos,
Vassilios Smyrniotis,
Nikolaos Arkadopoulos
Publication year - 2020
Publication title -
turkish journal of anaesthesiology and reanimation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 12
eISSN - 2667-677X
pISSN - 2667-6370
DOI - 10.5152/tjar.2019.81542
Subject(s) - resuscitation , creatinine , shock (circulatory) , medicine , hemodynamics , mean arterial pressure , blood urea nitrogen , saline , anesthesia , triiodothyronine , hydroxyethyl starch , kidney , acidosis , endocrinology , blood pressure , heart rate , thyroid
Apoptosis, measured via caspase activity, can be used to assess renal tissue damage in haemorrhagic shock. We investigated whether Triiodothyronine could attenuate apoptosis and protect against haemorrhagic shock-induced renal injury.