
Use of Gentamicin for Sepsis and Septic Shock in Anaesthesia-Intensive Care Unit: A Clinical Practice Evaluation
Author(s) -
Cyril Pernod,
Antoine Lamblin,
Andrei Cividjian,
P. Gérôme,
Wey Pierre-François
Publication year - 2020
Publication title -
turkish journal of anaesthesiology and reanimation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 12
eISSN - 2667-677X
pISSN - 2667-6370
DOI - 10.5152/tjar.2019.57255
Subject(s) - gentamicin , medicine , septic shock , context (archaeology) , sepsis , intensive care unit , anesthesia , medical prescription , cmax , loading dose , shock (circulatory) , intensive care , prospective cohort study , intensive care medicine , surgery , pharmacokinetics , antibiotics , pharmacology , chemistry , biochemistry , biology , paleontology
Numerous cases of gentamicin underdosing have been described in the literature in the context of sepsis and septic shock in anaesthesia-intensive care units (ICU). A survey of clinical practice was conducted with the aim to rationalise the use of gentamicin in the unit. The secondary objective was to propose a corrective formula for adjusting individual dosage.