Open AccessAssociation of genetic polymorphisms of glutamate decarboxylase 2 and the dopamine D2 receptor with obesity in Taiwanese subjects
Author(s) -
Ke-Chang Chen,
YiChen Lin,
Wen-Chii Chao,
Hsieh-Kun Chung,
Su-Sheng Chi,
Wensheng Liu,
WenTung Wu
Publication year - 2012
Publication title -
annals of saudi medicine/annals of saudi medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.373
H-Index - 44
eISSN - 0975-4466
pISSN - 0256-4947
DOI - 10.5144/0256-4947.2012.121
Subject(s) - medicine , general hospital , body mass index , obesity , tian , traditional medicine , pediatrics , ancient history , history
It has been proposed that glutamate decarboxylase 2 and the dopamine D2 receptor are involved in the brain reward cascade to increase carbohydrate craving and cause eating disorders. We investigated the association between the polymorphisms of the GAD2 and DRD2 genes and obesity with a higher body mass index (BMI) in Taiwanese patients.