Open AccessDifferential gene expression profiles of periodontal soft tissue from rat teeth after immediate and delayed replantation: a pilot study
Author(s) -
Yong Kwon Chae,
Seo Young Shin,
Sang Wook Kang,
Sung Chul Choi,
Ok Hyung Nam
Publication year - 2022
Publication title -
journal of periodontal and implant science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 26
eISSN - 2093-2286
pISSN - 2093-2278
DOI - 10.5051/jpis.2104300215
Subject(s) - replantation , tooth replantation , gene expression , vascular endothelial growth factor , medicine , angiogenesis , tumor necrosis factor alpha , dentistry , andrology , immunology , biology , gene , anatomy , vegf receptors , resorption , genetics , root resorption
In dental avulsion, delayed replantation usually has an uncertain prognosis. After tooth replantation, complex inflammatory responses promote a return to periodontal tissue homeostasis. Various types of cytokines are produced in the inflammatory microenvironment, and these cytokines determine the periodontal tissue response. This study aimed to identify the gene expression profiles of replanted teeth and evaluate the functional differences between immediate and delayed replantation.