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Sweet's Syndrome Limited on the Palms and Soles: A Case Report
Author(s) -
Jeehyun Lim,
Woo Young Sim,
Bark Lynn Lew
Publication year - 2021
Publication title -
annals of dermatology/annals of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.385
H-Index - 37
eISSN - 2005-3894
pISSN - 1013-9087
DOI - 10.5021/ad.2021.33.5.459
Subject(s) - medicine , palm , sweet's syndrome , dermatology , sweet syndrome , quantum mechanics , physics
Sweet's syndrome was first described as a reactive dermatosis characterized by sudden onset of fever, leukocytosis, and erythematous plaques infiltrated with neutrophils. Therefore, Sweet's syndrome is also known as acute febrile neutrophilic dermatosis. However, subsequently, it became clear that fever and neutrophilia in Sweet's syndrome vary depending on the case, and several other characteristics have been described. The lesions in Sweet's syndrome are typically observed not only in the limbs but also in the face, neck, and upper trunk. A 28-year-old female without a specific medical history presented in a hospital following the complaint of painful erythematous patches and pustules on her palms and soles. She had no previous history of palmoplantar pustulosis and other infections or malignancies. A skin biopsy showed diffuse dermal infiltration of neutrophils. Laboratory tests showed increased neutrophil count and erythrocyte sedimentation rate. After systemic corticosteroid administration was initiated, the lesions gradually disappeared. The patient was subsequently diagnosed with Sweet's syndrome according to histology, clinical feature, and response to treatment. However, there have been few reports of Sweet's syndrome confined to the individuals' palms and soles. According to the literatures, although the dorsum of the hand is frequently affected, the palmoplantar involvement as in our case appears to be rare.

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