Open AccessA Case Report of Multiple Capillary Hemangioma in a Chronic Myeloid Leukemia Patient Taking Tyrosine Kinase Inhibitors
Author(s) -
Hyun Jeong Byun,
Donghwi Jang,
Jong-Eun Lee,
Se Jin Oh,
Youn Hee Lim,
Ji-Hye Park,
DongYoun Lee
Publication year - 2021
Publication title -
annals of dermatology/annals of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.385
H-Index - 37
eISSN - 2005-3894
pISSN - 1013-9087
DOI - 10.5021/ad.2021.33.3.278
Subject(s) - medicine , capillary hemangioma , tyrosine kinase , angiogenesis , myeloid leukemia , tyrosine kinase inhibitor , hemangioma , pathology , infantile hemangioma , cancer research , myeloid , receptor , cancer
A capillary hemangioma is a vascular tumor with small capillary sized vascular channel. Multiple capillary hemangioma in relation with drugs have been rarely reported. Here in, we report a case of multiple capillary hemangioma in patient diagnosed with chronic myeloid leukemia who received tyrosine kinase inhibitors (TKIs). Histopathological findings have shown capillary proliferation in the upper dermis, which is consistent with capillary hemangioma. Since TKIs can paradoxically activate the MEK/ERK pathway which is required for angiogenesis, we presumed that the lesions as the cutaneous side effects of TKIs.