Open AccessDangerous triplet: Polycystic ovary syndrome, oral contraceptives and Kounis syndrome
Author(s) -
Nurdan Erol
Publication year - 2014
Publication title -
world journal of cardiology
Language(s) - English
Resource type - Journals
ISSN - 1949-8462
DOI - 10.4330/wjc.v6.i12.1285
Subject(s) - polycystic ovary , medicine , kounis syndrome , hyperandrogenism , androgen excess , hirsutism , metformin , metabolic syndrome , acute coronary syndrome , diabetes mellitus , endocrinology , gynecology , insulin resistance , myocardial infarction
Polycystic ovary syndrome is characterized by ovulatory dysfunction, androgen excess and polycystic ovaries and is associated with hypertension, diabetes, metabolic syndrome and cardiovascular events. Oral contraceptives constitute rst-line treatment, particularly when symptomatic hyperandrogenism is present. However, these drugs are associated with cardiovascular events and hypersensitivity reactions that pose problem in differential diagnosis and therapy. We present a 14 year-old female with polycystic ovary syndrome taking oral contraceptive and suffering from recurrent coronary ischemic attacks with increased eosinophils, and troponin levels suggesting Kounis syndrome.