
Heart failure with reduced, mildly reduced, or preserved left ventricular ejection fraction: Has reasoning been lost?
Author(s) -
Αndrew Xanthopoulos,
Grigorios Giamouzis,
John Skoularigis,
Filippos Triposkiadis
Publication year - 2022
Publication title -
world journal of cardiology
Language(s) - English
Resource type - Journals
ISSN - 1949-8462
DOI - 10.4330/wjc.v14.i7.438
Subject(s) - ejection fraction , medicine , cardiology , heart failure , stroke volume
Left ventricular (LV) ejection fraction (LVEF), defined as LV stroke volume divided by end-diastolic volume, has been systematically used for the diagnosis, classification, and management of heart failure (HF) over the last three decades. HF is classified as HF with reduced LVEF, HF with midrange or mildly reduced LVEF, and HF with preserved LVEF using arbitrary, continuously changing LVEF cutoffs. A prerequisite for using this LVEF-based terminology is knowledge of the LVEF normal range, which is lacking and may lead to erroneous conclusions in HF, especially at the higher end of the LVEF spectrum.