Open AccessBreast metastasis from rectal carcinoma: A case report and review of the literature
Author(s) -
Dan Wang,
Su Jin Yang,
Wei Xian Chen
Publication year - 2021
Publication title -
malawi medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 18
eISSN - 1995-7270
pISSN - 1995-7262
DOI - 10.4314/mmj.v33i3.11
Subject(s) - medicine , metastasis , colorectal cancer , breast cancer , malignancy , radiation therapy , adenocarcinoma , histopathology , irinotecan , breast carcinoma , asymptomatic , oncology , cancer , pathology
BackgroundMetastasis from extramammary primary tumor to breast is extremely rare. Case SummaryA 59-year-old woman with 1-year history of rectal cancer presented with asymptomatic breast mass. At 16 months after the diagnosis of rectal mucinous adenocarcinoma, a breast mass was confirmed by ultrasonography and identified by pathology and immunohistochemistry as a metastasis from the rectal cancer. Treatments included chemotherapy (6 cycles: 300 mg irinotecan on day 1, 4.5 mg raltitrexed on day 2, 450 mg bevacizumab on day 3), radiotherapy, and surgical resection. Two years of follow-up examinations (6-months intervals) showed no evidence of recurrence or novel distant metastasis. ConclusionBreast metastasis from rectal carcinoma is a rare secondary malignancy. Final diagnosis can be established by histopathology and immunohistochemistry.