Open AccessThe report of cardiomyopathy and mid aortic syndrome in a HIV infected child
Author(s) -
Manolya Kara
Publication year - 2020
Publication title -
malawi medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 18
eISSN - 1995-7270
pISSN - 1995-7262
DOI - 10.4314/mmj.v32i2.8
Subject(s) - medicine , myocarditis , cardiomyopathy , autoimmunity , zidovudine , complication , immunology , human immunodeficiency virus (hiv) , cardiology , antibody , viral disease , heart failure
Cardiomyopathy is a serious complication of Human Immunodeficiency virus (HIV) infection. Direct effects of HIV, cardiac autoimmunity, opportunistic infections (OIs), nutritional deficiencies (selenium) and severe immunesuppression have been implemented for HIV related cardiomyopathy (HIVAC) ; Elevated anti-alpha myosin antibodies in HIV infection cause cardiac autoimmunity, selenium deficiency leads to cardiomyopathy, myosite invasion and cytokine release cause myocarditis whereas zidovudine triggers reversible and dose dependent myocyte toxicity.