Open AccessA case of acute megakaryoblastic leukaemia (FAB M7), a rare type of acute myeloid leukemia (AML), in a teenager
Author(s) -
PO Olatunji,
Omotola Toyin Ojo,
Fatai O Bello,
Binta Y Bakare,
AO Olatunji
Publication year - 2018
Publication title -
malawi medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.43
H-Index - 18
eISSN - 1995-7270
pISSN - 1995-7262
DOI - 10.4314/mmj.v30i4.15
Subject(s) - medicine , acute megakaryoblastic leukemia , immunophenotyping , myeloid leukemia , bone marrow , bone marrow examination , leukemia , myeloid , acute leukemia , immunology , antigen
Acute Megakaryoblastic Leukaemia (AML, M7) is a rare type of acute myeloid leukemia (AML) evolving from primitive megakaryoblasts. It accounted for 1.2% of newly diagnosed AML according to Eastern Cooperative Oncology Group (ECOG) trials between 1984 and 1997. Patients may present with a broad variety of symptoms including low-grade fever, easy bruising, and life-threatening conditions. We report a rare case of AML, M7 in a 19-year-old lady who presented with weakness and fatigue. She was diagnosed as a case of AML, M7 on the basis of peripheral blood finding, bone marrow examination report, radiological findings and immunophenotyping.