Open AccessTriterpenoids from the spores of Ganoderma lucidum
Author(s) -
BingJi Ma,
Wei Ren,
Yan Zhou,
Jinlong Ma,
Yuan Ruan,
ChunNan Wen
Publication year - 2011
Publication title -
north american journal of medical sciences
Language(s) - English
Resource type - Journals
eISSN - 2250-1541
pISSN - 1947-2714
DOI - 10.4297/najms.2011.3495
Subject(s) - ganoderma , ganoderma lucidum , spore , triterpenoid , traditional medicine , biology , medicine , botany
Recently a series of triterpenoids were isolated from ganoderma spores and have drawn the attention of chemists and pharmacists. The aim of this review is to summarize the triterpenoids and their bioactivities of ganoderma spores. The chemical and biological literatures of ganoderma spores dealing with the structural analysis and bioactivity assay were selected. Triterpenoids isolated from ganoderma spores showed significantly anti-HIV-1 protease, anti-tumor, and anti-complement activities. Triterpenoids are the main active constituents of ganoderma spores and show various bioactivities for its medicinal use. In addition, biological activities of ganoderma spores still need further assessment before they can be accepted not only by the traditional Asian medicine community, but also by western science and medicine.