Open AccessCytotoxic T lymphocytes mediate chronic inflammation of the nasal mucosa of patients with atypical allergic rhinitis
Author(s) -
Shuqi Qiu,
Yun Du,
Xiaobei Duan,
Xinyu Geng,
Jianxiong Xie,
Han Gao,
PingChang Yang
Publication year - 2011
Publication title -
north american journal of medical sciences
Language(s) - English
Resource type - Journals
eISSN - 2250-1541
pISSN - 1947-2714
DOI - 10.4297/najms.2011.3378
Subject(s) - immunology , cytotoxic t cell , antigen , cd80 , medicine , immune system , cd8 , antigen presenting cell , cd86 , t cell , dendritic cell , biology , cd40 , biochemistry , in vitro
The prevalence of chronic rhinitis is increasing rapidly; its pathogenesis is to be further understood; immune inflammation is one of the possible causative factors. Antigen specific CD8+ T cells play a critical role in the induction of chronic inflammation.