Open AccessOverview of drug induced liver injury in Brazil: What is the role of public health policy on the evidence?
Author(s) -
Matheus William Becker,
Karin Hepp Schwambach,
Michele John Muller Lunardelli,
Carine Raquel Blatt
Publication year - 2021
Publication title -
world journal of gastrointestinal pharmacology and therapeutics
Language(s) - English
Resource type - Journals
ISSN - 2150-5349
DOI - 10.4292/wjgpt.v12.i3.40
Subject(s) - medicine , pharmacovigilance , public health , pyrazinamide , epidemiology , liver injury , tuberculosis , rifampicin , intensive care medicine , liver transplantation , drug , hepatitis , environmental health , medical prescription , pharmacology , transplantation , pathology
Adverse drug reactions are responsible for increased costs and morbidity in the health system. Hepatotoxicity can be induced both by non-prescription drugs and by those used for chronic diseases. It is the main cause of safety-related drug marketing withdrawals and could be responsible for irreversible and fatal injuries.