Open AccessThe Value of 18F-FDG PET/CT Imaging in the Evaluation of Interim Neoadjuvant Chemotherapy Response in Locally Advanced Breast Cancer
Author(s) -
Gamze Tatar,
Özlem Özkul,
Göksel Alçın
Publication year - 2022
Publication title -
molecular imaging and radionuclide therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.292
H-Index - 7
eISSN - 2147-1959
pISSN - 2146-1414
DOI - 10.4274/mirt.galenos.2022.44154
Subject(s) - standardized uptake value , medicine , breast cancer , nuclear medicine , positron emission tomography , primary tumor , radiology , cancer , metastasis
Neoadjuvant chemotherapy (NAC) is the frequently used treatment option for locally advanced breast cancer (LABC). This study investigated the potential value of 18 fluorine-fluorodeoxyglucose ( 18 F-FDG) positron emission tomography/computed tomography (PET/CT) to estimate the pathological complete response (pCR) using maximum standardized uptake value (SUV max ) and change (ΔSUV max ) after 3-4 cycles of NAC. Additionally, it was established the relationship between PET/CT imaging findings and histopathological features in LABC patients whose treatment response was evaluated with interim PET/CT.