Open AccessChanges of cell membrane fluidity for mesenchymal stem cell spheroids on biomaterial surfaces
Author(s) -
ChuiWei Wong,
Hao-Wei Han,
Shanhui Hsu
Publication year - 2022
Publication title -
world journal of stem cells
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.907
H-Index - 18
ISSN - 1948-0210
DOI - 10.4252/wjsc.v14.i8.616
Subject(s) - spheroid , mesenchymal stem cell , vesicle , membrane fluidity , membrane , biophysics , cell , cell membrane , microbiology and biotechnology , chemistry , biology , in vitro , biochemistry
The therapeutic potential of mesenchymal stem cells (MSCs) in the form of three-dimensional spheroids has been extensively demonstrated. The underlying mechanisms for the altered cellular behavior of spheroids have also been investigated. Cell membrane fluidity is a critically important physical property for the regulation of cell behavior, but it has not been studied for the spheroid-forming cells to date.