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Cancer stem cells (CSCs) have been implicated in tumorigenesis and tumor recurrence and metastasis are key therapeutic targets in cancer treatment. MicroRNAs display therapeutic potential by controlling the properties of CSCs; however, whether an association exists between miR-3682-3p and CSCs is unknown.

world journal of stem cells

miR-3682-3p directly targets FOXO3 and stimulates tumor stemness in hepatocellular carcinoma <i>via </i>a positive feedback loop involving FOXO3/PI3K/AKT/c-Myc

miR-3682-3p directly targets FOXO3 and stimulates tumor stemness in hepatocellular carcinoma via a positive feedback loop involving FOXO3/PI3K/AKT/c-Myc