Open AccessCombination of preoperative fibrinogen and D-dimer as a prognostic indicator in pancreatic ductal adenocarcinoma patients undergoing R0 resection
Author(s) -
Lipeng Zhang,
Hanyun Ren,
Yongxing Du,
Xiaohao Zheng,
Zongming Zhang,
Chengfeng Wang
Publication year - 2021
Publication title -
world journal of gastrointestinal surgery
Language(s) - English
Resource type - Journals
ISSN - 1948-9366
DOI - 10.4240/wjgs.v13.i3.279
Subject(s) - medicine , pancreatic ductal adenocarcinoma , d dimer , fibrinogen , surgery , adenocarcinoma , resection , pancreatic cancer , radiology , cancer
Patients with malignant tumors frequently exhibit hyperactivation of the coagulation system and secondary increased fibrinolytic activity. Fibrinogen and D-dimer are common indicators that are crucial in the coagulation/fibrinolysis system. Both indicators have been verified to have predictive value in the overall survival (OS) of many patients with solid malignancies.