Open AccessRole of an acidic environment in the treatment of diabetic foot infections: A review
Author(s) -
Basavraj Nagoba,
Ajay Gavkare,
Abhijit Rayate,
Sachin Mumbre,
Arunkumar Rao,
Basavraj Warad,
Neeta Nanaware,
Nawab Jamadar
Publication year - 2021
Publication title -
world journal of diabetes
Language(s) - English
Resource type - Journals
ISSN - 1948-9358
DOI - 10.4239/wjd.v12.i9.1539
Subject(s) - medicine , antiseptic , diabetic foot , intensive care medicine , wound care , biguanide , diabetes mellitus , pharmacology , surgery , metformin , pathology , endocrinology
Management of diabetic foot ulcers is the biggest challenge to the clinician, as conventional antibiotic therapies and local wound care have their own limitations. They are not effective for control of infections and promotion of healing because of cytotoxic effects. In view of cytotoxicity of routinely used topical antiseptic agents, this article focuses on the search of an ideal topical antiseptic agent that is safe and effective in controlling infectious agents and also in promoting the healing process. This review focuses on the use of various acids such as citric, acetic, hyaluronic, and hypochlorous acids as topical agents in diabetic foot infections. This article also focuses on the different roles of acids in the treatment of diabetic foot infections.