Open AccessEndothelin receptor antagonists for the treatment of diabetic nephropathy: A meta-analysis and systematic review
Author(s) -
Li Zhang,
Shuai Xue,
Jie Hou,
Guang Chen,
Zhenhe Xu
Publication year - 2020
Publication title -
world journal of diabetes
Language(s) - English
Resource type - Journals
ISSN - 1948-9358
DOI - 10.4239/wjd.v11.i11.553
Subject(s) - medicine , meta analysis , diabetic nephropathy , endothelin receptor , diabetes mellitus , bioinformatics , receptor , pharmacology , endocrinology , biology
Diabetic nephropathy (DN) is the main cause of chronic kidney disease and end-stage renal disease worldwide. Although available clinical trials have shown that endothelin receptor (ER) antagonists may be a novel and beneficial drug for DN, no consistent conclusions regarding their sufficient effectiveness and safety for patients with DN have been presented.